FAS -670A>G promoter polymorphism is associated with soluble Fas levels in primary Sjögren’s syndrome
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چکیده
منابع مشابه
Aqueous Humor Levels of Soluble Fas and Fas-ligand in Patients with Primary Open Angle and Pseudoex-foliation Glaucoma
Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...
متن کاملaqueous humor levels of soluble fas and fas-ligand in patients with primary open angle and pseudoex-foliation glaucoma
background: glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. in patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. death of the trabecular meshwork cells may be a result of apoptosis. objective: to investigate the aqueous humor levels of soluble fas (sfas) and fas-ligand (sfasl) in ...
متن کاملFas/APO-1 promoter polymorphism is not associated with non-melanoma skin cancer.
Introduction NMSC incidence is increasing at an alarming rate (1), and the majority of NMSC is likely attributable to UV exposure. An important biological effector of UV exposure is the Fas receptor, which in cooperation with Fas ligand induces apoptosis in keratinocytes after UV exposure (2). The gene encoding Fas, TNFRSF6, contains a promoter single nucleotide polymorphism at position 2670 th...
متن کاملFas/FasL promoter gene polymorphism in patients with rheumatoid arthritis.
OBJECTIVES Fas/FasL is significantly involved in the pathogenesis of rheumatoid arthritis (RA). Fas/FasL gene polymorphism may be associated with susceptibility to rheumatoid arthritis and disease severity. AIM To investigate the Fas 670 G/A and FasL 843 C/T genotype and allele frequency in patients with RA, and determine its potential association with susceptibility to the disease and the cl...
متن کاملAqueous humor levels of soluble Fas and Fas-ligand in patients with primary open angle and pseudoexfoliation glaucoma.
BACKGROUND Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glaucoma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. OBJECTIVE To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in g...
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ژورنال
عنوان ژورنال: Genetics and Molecular Research
سال: 2014
ISSN: 1676-5680
DOI: 10.4238/2014.july.2.12